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Hynda K Kleinman Selected Research

laminin 1

12/2011The potent peptide antagonist to angiogenesis, C16Y, and cisplatin act synergistically in the down-regulation of the Bcl-2/Bax ratio and the induction of apoptosis in human ovarian cancer cells.
8/2003Identification of a potent peptide antagonist to an active laminin-1 sequence that blocks angiogenesis and tumor growth.
10/2002Ile-Lys-Val-Ala-Val (IKVAV)-containing laminin alpha1 chain peptides form amyloid-like fibrils.
9/2002Metallothionein promotes laminin-1-induced acinar differentiation in vitro and reduces tumor growth in vivo.
6/2002The B16F10 cell receptor for a metastasis-promoting site on laminin-1 is a heparan sulfate/chondroitin sulfate-containing proteoglycan.

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Hynda K Kleinman Research Topics

Disease

31Neoplasms (Cancer)
08/2021 - 06/2002
17Neoplasm Metastasis (Metastasis)
01/2020 - 06/2002
10Wounds and Injuries (Trauma)
10/2019 - 01/2003
7Melanoma (Melanoma, Malignant)
04/2016 - 06/2002
6Inflammation (Inflammations)
10/2019 - 06/2002
5Breast Neoplasms (Breast Cancer)
08/2005 - 08/2002
3Dry Eye Syndromes (Dry Eye Syndrome)
07/2018 - 01/2015
3Ovarian Neoplasms (Ovarian Cancer)
12/2011 - 08/2002
3Carcinogenesis
03/2011 - 12/2003
2Cicatrix (Scar)
10/2019 - 01/2012
2Brain Neoplasms (Brain Tumor)
04/2016 - 12/2002
2Hypoxia (Hypoxemia)
01/2015 - 11/2010
2Infections
10/2012 - 04/2006
2Colonic Neoplasms (Colon Cancer)
03/2011 - 11/2010
2Ischemia
06/2010 - 05/2003
2Giant Cell Arteritis (Horton Disease)
05/2003 - 09/2002
1Varicose Ulcer (Ulcer, Venous)
10/2019
1Epidermolysis Bullosa
10/2019
1Pruritus (Itching)
10/2019
1Pressure Ulcer (Bedsore)
10/2019
1Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis)
01/2017
1Myalgia
01/2017
1Dermatitis
01/2017
1Eye Injuries (Eye Injury)
08/2015
1Corneal Injuries
01/2012
1Fibrosis (Cirrhosis)
01/2012
1Carcinoma (Carcinomatosis)
03/2011
1Liver Neoplasms (Liver Cancer)
03/2011
1Lung Neoplasms (Lung Cancer)
03/2011
1Esophageal Squamous Cell Carcinoma
03/2011
1Esophageal Neoplasms (Esophageal Cancer)
03/2011
1Colorectal Neoplasms (Colorectal Cancer)
03/2011
1Osteosarcoma (Osteogenic Sarcoma)
03/2011
1Fibrosarcoma
03/2010
1Kaposi Sarcoma (Kaposi's Sarcoma)
04/2006

Drug/Important Bio-Agent (IBA)

13Peptides (Polypeptides)IBA
01/2013 - 06/2002
8ThymosinIBA
10/2019 - 11/2003
6thymosin beta(4)IBA
04/2010 - 01/2003
5matrigelIBA
08/2021 - 10/2005
5laminin 1IBA
12/2011 - 06/2002
4Proteins (Proteins, Gene)FDA Link
10/2019 - 04/2004
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2010 - 06/2004
4Laminin (Merosin)IBA
12/2009 - 06/2002
3Pharmaceutical PreparationsIBA
01/2015 - 08/2002
3Peptide Hydrolases (Proteases)FDA Link
01/2013 - 11/2002
3AG 73IBA
03/2008 - 06/2002
3Estrogens (Estrogen)FDA Link
06/2004 - 06/2002
2Cyclosporine (Ciclosporin)FDA LinkGeneric
07/2018 - 08/2015
2LectinsIBA
04/2016 - 09/2002
2CollagenIBA
01/2015 - 01/2003
2HydrogelsIBA
12/2014 - 01/2003
2Interleukin-6 (Interleukin 6)IBA
04/2013 - 05/2003
2SyndecansIBA
01/2013 - 03/2007
2isoleucyl-lysyl-valyl-alanyl-valineIBA
01/2013 - 10/2002
2Cisplatin (Platino)FDA LinkGeneric
12/2011 - 03/2008
2Angiogenic ProteinsIBA
12/2011 - 07/2006
2laminin AIBA
01/2008 - 06/2002
2Proteoglycans (Proteoglycan)IBA
03/2007 - 06/2002
2AcidsIBA
10/2006 - 07/2006
2Matrix Metalloproteinases (MMPs)IBA
07/2006 - 11/2003
2Heparitin Sulfate (Heparan Sulfate)IBA
11/2005 - 06/2002
2laminin alpha5IBA
11/2005 - 07/2004
2heparanaseIBA
04/2005 - 12/2003
2Estrogen ReceptorsIBA
06/2004 - 12/2003
2Messenger RNA (mRNA)IBA
12/2003 - 11/2003
1CytokinesIBA
10/2019
1MucinsIBA
07/2018
1diquafosolIBA
07/2018
1lifitegrastIBA
07/2018
1Prescription DrugsIBA
07/2018
1Immunoglobulin A (IgA)IBA
01/2017
1Gemfibrozil (Lopid)FDA LinkGeneric
01/2017
1LipidsIBA
01/2017
1Plasminogen Activator Inhibitor 2IBA
04/2016
1Doxycycline (Periostat)FDA LinkGeneric
08/2015
1Paclitaxel (Taxol)FDA LinkGeneric
01/2015
1Bovine Serum AlbuminIBA
01/2015
1Glucose (Dextrose)FDA LinkGeneric
01/2015
1Fluorouracil (Carac)FDA LinkGeneric
01/2015
1Scopolamine (Hyoscine)FDA Link
01/2015
1Proto-Oncogene Proteins c-sis (Platelet Derived Growth Factor B)IBA
04/2013
1Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA
04/2013
1TNF Receptor-Associated Factor 1IBA
04/2013
1tyrosyl-isoleucyl-glycyl-seryl-arginineIBA
01/2013
1IntegrinsIBA
01/2013
1SteroidsIBA
10/2012
1Antineoplastic Agents (Antineoplastics)IBA
12/2011
1Isoniazid (Ftivazide)FDA LinkGeneric
06/2010
1Niacin (Nicotinic Acid)FDA LinkGeneric
06/2010
1Oxygen (Dioxygen)IBA
06/2010
1Interleukin-1 (Interleukin 1)IBA
03/2010
1Interleukin-12 (IL 12)IBA
03/2010
1Laminin ReceptorsIBA
12/2009
1Green Fluorescent ProteinsIBA
12/2009
1Microfilament Proteins (Actin Binding Proteins)IBA
10/2006
1Metalloproteases (Metalloproteinases)IBA
07/2006
1VaccinesIBA
04/2006

Therapy/Procedure

5Therapeutics
01/2020 - 03/2010
1Hematopoietic Stem Cell Mobilization
10/2012
1Lasers (Laser)
12/2009